UT College of Pharmacy
|
PURPOSE: The Center for Applied is a consortium of academic and hospital-based investigators with major interests in the relationship between drug disposition and drug dynamics. The Center was founded through the joint efforts of The University of Toledo and St. Vincent Medical Center in December, 1990. 
The Center for Applied Pharmacology conducts clinical investigations pertaining to:
Center personnel are specialized in theoretical and applied pharmacokinetics, drug metabolism and disposition, and drug utilization review. Support personnel include various medical specialists, experienced clinical pharmacists, research nurses, and laboratory technologists. KENNETH BACHMANN, Ph.D., F.C.P. Director, Distinguished University Professor of Pharmacology, The University of Toledo. Dr. Bachmann's interest is in drug disposition, particularly drug metabolism. Most of his research deals with the study of factors which affect drug disposition, e.g. age, disease, concomitant drug use, and exposure to environmental chemicals. These interactions are studied in both mechanistic and pharmacokinetic contexts. LUIS JAUREGUI, M.D. Director, Chief, Infectious Diseases, Clinical Professor of Medicine and Microbiology, St. Vincent Medical Center. Dr. Jauregui has expertise in internal medicine and infectious diseases. He continues to be principal investigator or coinvestigator on numerous sponsored research projects encompassing Phases 1, 2, and 3 of new drug testing. ROBERT BELLOTO Jr., Ph.D. Assistant Professor of Pharmacology, The University of Toledo. Dr. Belloto earned his doctorate at Ohio State University. His research encompasses pharmacokinetic theory, modeling, and applied pharmacokinetics. DONALD B. WHITE, Ph.D. Associate Professor of Mathematics and Pharmacology and Head of the Statistics Group, The University of Toledo. Dr. White taught at the University of California at Irvine and the State University of New York at Buffalo before accepting his present position. Dr. White's interests include statistical theory concerning pharmacokinetic data, population kinetics, and quantitative prediction of the phenomenon of synergy of drug mixtures. 
DARLA SCOTT, R.N.,C.C.R.C.KRISTEN MILLER, B.S.N., R.N., C.C.R.C. MARY E. SCOTT, B.S.N., R.N., C.C.R.C. TINA STEINHAUSER, R.N.,C.C.R.C. MOLLY MCCORMICK, R.N.,C.C.R.C. The clinical research nurses were originally specialized in critical care, and are all certified in clinical research. studies. MEDICAL SPECIALISTS:
FACILITIES:The Center for Applied Pharmacology has facilities in Toledo, Ohio. Laboratory space and equipment at the University of Toledo are currently available for conducting analytical work. Measurements of drugs and metabolites in biological samples con be performed using fluorescent polarization immunoassay (FPIA), gas chromatography (GC), and high performance liquid chromatography (HPLC). Through a strategic alliance agreement virtually any type of analytical work including LC/MS/MS can be undertaken at the comprehensive laboratories of Ricerca, LLC, which is a GLP certified laboratory. Physical examinations are performed by M.D.s and clinical laboratory measurements are performed by the certified laboratory at St. Vincent Medical Center. The Medical Center is also the inpatient and outpatient performance site for drug administration, drug sampling, and subject observation. Skilled nurses experienced in the conduct of clinical drug trials participate fully throughout each investigation. Computer analyses can be performed using conventional pharmacokinetic and statistical software operating on either the University of Toledo mainframe computers or microcomputers. Studies are not initiated without approval from the Human Subjects Committees of cooperating institutions. REPORTS: Results of clinical investigations are provided in a timely manner. Copies of all records are maintained on file by The Center for Applied Pharmacology, and are available for audit by appropriate Institutional Review Boards and sponsors. References to specific subjects or patients are codified so that identities always remain confidential. Manuscripts intended for publication will be sent to contractors prior to journal submission as a matter of courtesy. The suitability of data for publication is an issue which must be negotiated and agreed to prior to the initiation of any investigation by The Center for Applied Pharmacology. COSTS: The Center for Applied Pharmacology is an academically oriented consortium of investigators interested in conducting clinical investigations of pharmacokinetic and pharmacodynamic interest. It is interested in conducting such investigations cost- effectively. Each project budget is negotiated separately, but basically The Center for Applied Pharmacology will charge only enough to recover costs for supplies, clinical personnel, laboratory tests, physical examinations, and technical help. A modest overhead charge will be added. For extensive projects some salary offset of a principal investigator may be necessary. INQUIRIES: For more information, bibliographies of consortium members, or recent work, etc., please contact:
|
College of Pharmacy • The University of Toledo • 2801 W. Bancroft •
Toledo, OH 43606-3390 • 419.530.1904
© 2006-2008 UT College of Pharmacy • All rights reserved. • Send all feedback / comments to webmaster.
© 2006-2008 UT College of Pharmacy • All rights reserved. • Send all feedback / comments to webmaster.